Life Extension Senolytic Activator® combines black tea theaflavins, the plant-derived flavonoid apigenin, and ultra-absorbable forms of the bio-flavonoids quercetin and fisetin to support the burden of aging senescent cells and support systemic rejuvenation.
Cellular senescence is a natural part of the aging process in which cells no longer function optimally. Senescent cells can accumulate over time, affecting the day-to-day function of the healthy cells around them.
Senolytic compounds selectively support senescent cells. New research indicates that black tea theaflavins and quercetin support specific biological pathways, so that the body to manage senescent cells.
Theaflavins are compounds derived from Camellia sinensis (tea plant). These compounds have widespread health benefits, supporting healthy cell division and healthy immune response within the cells.
New research indicates that theaflavins may be especially helpful for supporting senescent cell burden.
Quercetin supports endothelial and cardiovascular health, supports healthy immune function and more. The value of quercetin has been recognized for some time, but its potential to meaningfully support whole body rejuvenation is just starting to be uncovered through its senolytic activity. The discovery that quercetin is a senolytic compound has drawn significant attention to this innovative approach to support healthy aging.
Standard quercetin is hard to absorb. But this formulation features our new quercetin phytosome, a phospholipid sphere that encases the quercetin, aiding in its absorption and making it up to 50 times more bioavailable.
Fisetin is terrific for whole-body health. It’s a powerful senolytic compound, meaning it actively supports senescent cells, the ones that no longer function optimally. Fisetin supports the body’s natural pathways for clearing senescent cells, which allows healthy cells to flourish.
Another important aspect of healthy cellular aging is sirtuin function. Sirtuin proteins keep your cells performing at their best — but sirtuin activity declines with age. Fisetin has been shown in research to support youthful, healthy sirtuin function. During digestion, much of fisetin is rapidly converted into other compounds by a process called conjugation. To overcome this, this formular combines fisetin with galactomannans, a type of fibre derived from fenugreek seed. Doing so makes it up to 25 times more readily available than standard fisetin.That means it circulates in your system longer and your body has more time to access fisetin’s many health benefits.
Life Extension has identified apigenin, a natural flavonoid, as a powerful addition to Senolytic Activator® formula. Quercetin and theaflavins from black tea support some senescent cells, but not all of them. The remaining senescent cells create compounds known collectively as Senescence Associated Secretory Phenotype, or SASP. Apigenin supports youthful levels of SASP from remaining senescent cells, to support cellular and tissue health—a critical aspect of healthy aging.
For those who aren’t keen on adding another supplement to their regimen, here’s good news: healthy aging research indicates that intermittent dosing is good support for healthy aging.
Senolytic Activator® instructions call for taking just three vegetarian capsules, once a week.
Support healthy levels of senescent cells, healthy cellular function and healthy aging with Senolytic Activator®.